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However, an INMT found in rabbit lung was proven to have a Considerably bigger Km (270 uM, Thompson and Weinshilboum, 1998; 340 uM, Raisanen and Karkkainen, 1978) as opposed to brain enzyme in rats. This recommended that INMT could exist in many isoenzyme forms amongst species And maybe even inside the identical animal, each possessing various Km's